Li began his career in the comics industry in 1982. After working for a corporate comics publisher in Hong Kong for a month, he decided to start his own venture as a freelancer. Following on from the release of The Wisely series, he self-published Tong Men Shao Nian, a prominent title which rocketed him to fame in 1987. He has since developed a distinctive art style, creating his own visual world with eerily experimental works that broke genre rules.